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Effects of non-surgical periodontal therapy (NSPT) in prediabetes patients with periodontitis - A randomised control trial

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Original Article

Author Details : G Sreenivasulu*, Krishnan Vishwanathan, K A Ravivarma Prasad, Kacharla Sowjanya, Anitha R, Deepthi P

Volume : 4, Issue : 2, Year : 2022

Article Page : 85-92

https://doi.org/10.18231/j.jdp.2022.017

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Abstract

Aim: To clinically and microbiologically evaluate the association of periodontitis and pre-diabetes.
Materials and Methods: The trial was designed as a randomized controlled clinical trial with a sample size of total of 100 with 1:1 gender ratio. Test group taken were patients with chronic periodontitis with prediabetes and Control group were patients with periodontitis without prediabetes. Body mass index (BMI), Periodontal Probing Depth (PPD),Bleeding on probing (BOP),Clinical Attachment Loss(CAL) using UNC colour coded periodontal probe were recorded. The microbial load in pre-diabetes patients was assessed using samples collected from the periodontal pockets ?5mm. Fasting Blood sugar (FBS), Post Prandial blood sugar (PPBS), Fasting Insulin were recorded at baseline, 6 weeks,12 weeks and after Non-surgical periodontal therapy (SRP) after taking consent from the patient. The data collected were entered into Microsoft excel 2018. Statistical analysis was done using IBM SPSS Statistics for Windows, Version 27.0. Armonk, NY: IBM Corp. Descriptive analyses were done. Student’s t-test, repeated measures of ANOVA were used for determination of the significance of HOMA-IR, HOMA- β mean differences between and within the groups.
Results: In both test and control groups, there was a significant difference (p<0> Conclusion: There is a significant association between prediabetes state and periodontitis. Early diagnosis of periodontitis and a proper treatment in prediabetic group can prevent the progression of prediabetic condition to diabetes and vise versa.
 
Keywords: Periodontitis, Prediabetes, Insulin resistance, β cell dysfunction

How to cite : Sreenivasulu G, Vishwanathan K, Prasad K A R, Sowjanya K, Anitha R, Deepthi P, Effects of non-surgical periodontal therapy (NSPT) in prediabetes patients with periodontitis - A randomised control trial. J Dent Panacea 2022;4(2):85-92

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