The Journal of Dental Panacea
Official Publication of Dental Panacea
Official Publication of Dental Panacea
Online ISSN: 2348-8727
CODEN : JDP
The Journal of Dental Panacea (JDP) open access, peer-reviewed quarterly journal, Publish quarterly as Open Access (OA). Vision of this journal for better dissemination of knowledge, Journal will be publishing the article ‘Ahead of Print’ immediately on acceptance. In addition, the journal would allow free access (Open Access) to its contents, which is likely to attract more readers and citations to articles published in JDP. Manuscripts must be prepared in accordance with “Uniform requirements” of the The Journal of Dental Panacea as more...Original Article
Author Details :
Volume : 6, Issue : 2, Year : 2024
Article Page : 103-106
https://doi.org/10.18231/j.jdp.2024.020
Abstract
Background: Trigeminal neuralgia (TN) is an extremely debilitating neuropathic pain in which Carbamazepine (CBZ) is the preferred drug of choice in pharmacological management and surgical intervention to be considered only when drug therapy proves ineffective. However, it’s long-term use leads to refraction along with severe side effects has made to search for a suitable alternative to CBZ.
Aim & Objective: Present study was conducted to evaluate the effectiveness of Oxcarbazepine (OXC) in those patients, who failed to get adequate relief despite taking CBZ for longer span.
Materials and Methods: 15 patients including 12 males and 3 females (age group 30-65 years) mean age 53.3 years were prescribed OXC in subsequent doses of 300mg, 600mg, 900mg, maximum up to 2400mg and the pain relief was analysed using grading as No response, Moderate and Excellent response.
Observations: Significant pain relief was observed as the dose was increased in the range of 1200-2400mg. Likert scale (5 points scale) for treatment satisfaction was used in which 2 patients marked as very satisfied, 11 patients were found to be satisfied, whereas only 2 marked as neither satisfied nor dissatisfied.
Conclusion : OXC, proves to be a useable alternative to CBZ in terms of being cost effective, better pain control and less side effects. A brief review of the drug OXC is also added.
Keywords: Trigeminal Neuralgia, Oxcarbazepine, Carbamazepine, Refractory pain
How to cite : Singla N, Oxcarbazepine: A usable alternative to carbamazepine in the treatment of trigeminal neuralgia- A pilot study and drug review. J Dent Panacea 2024;6(2):103-106
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution 4.0 International License, which allows others to remix, and build upon the work, the licensor cannot revoke these freedoms as long as you follow the license terms.
