The Journal of Dental Panacea

Online ISSN: 2348-8727

CODEN : JDP

The Journal of Dental Panacea (JDP) open access, peer-reviewed quarterly journal, Publish quarterly as Open Access (OA).  Vision of this journal  for better dissemination of knowledge, Journal will be publishing the article ‘Ahead of Print’ immediately on acceptance. In addition, the journal would allow free access (Open Access) to its contents, which is likely to attract more readers and citations to articles published in JDP. Manuscripts must be prepared in accordance with “Uniform requirements” of the The Journal of Dental Panacea as more...

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Get Permission Ahuja: Mucormycosis –An indelible black spot of COVID 19

The second wave of Covid 19 has drowned lives of many people all over the earth and still is unstoppable. Each and every day in the life of millennials is full of fear, worry and stress. Days and nights in this dreadful time are full of unexpected negative news a propos this monster ‘CORONA’. Steroid-full body of corona recovered patients have become immunocompromised with their ability to fight against general and oral infections. Consequently, one new complication is on rise, Mucormycosis. It is also known as ‘black fungus’. Mucormycosis or Zygomycosis is a rare but deadly fungal infection caused by a fungus mucormycete which is abundant in the environment. This fungus is found everywhere and generally harmless but life threatening in people with low immunity conditions like diabetes, patients on immunosuppressive drugs, steroids, anti-cancer therapy etc.1, 2

The signs and symptoms of this disease depend upon the site where infection is brewing:1

  1. Rhinocerebral (sinus and brain) mucormycosis may include: One-sided facial swelling, headache, toothache, jaw pain, nasal or sinus congestion, black lesions on nasal bridge or upper inside of mouth that quickly become more severe and fever

  2. Pulmonary (lung mucormycosis may include: Fever, cough, chest pain, Shortness of breath

  3. Cutaneous (skin) mucormycosis may include blisters or ulcers, and the infected area which turns black. Other symptoms include pain, warmth, excessive redness, or swelling around a wound.

  4. Gastrointestinal mucormycosis may include abdominal pain, nausea and vomiting and gastrointestinal bleeding

  5. Disseminated mucormycosis typically occurs in people who are already sick from other medical conditions, so it can be difficult to know which symptoms are related to mucormycosis. Patients with disseminated infection in the brain can develop mental status changes or coma.

Sources and traits:2

The fungus is most commonly found in decaying organic matter, such as leaves, compost piles, and animal dung. These molds thrive all over the environment and are commonly seen in soil, damp wall and old buildings. Infection can occur after someone inhales the spores from the air. People get mucormycosis through contact with fungal spores in the environment. A skin infection can occur after the fungus enters the skin through a burn, or skin injury. Infection of the oral cavity or brain is the most common forms of mucormycosis. One evident feature of this infection is fungal invasion into the blood vessels which results in the formation of blood clots and surrounding tissue death due to a loss of blood supply.

Prevention and Management:1

Prevention

Protecting yourself from the environment is the only way to prevent mucomycosis. Avoid areas with a lot of dust like construction or excavation sites or by wearing an N95 respirator mask in these areas. Avoid direct contact with water-damaged buildings and flood water after hurricanes and natural disasters; Avoid activities that involve close contact to soil or dust, such as yard work or gardening. Wear gloves, shoes, long pants and long sleeve shirt while in close contact with soil, damp wall and wooded areas. Regular cleaning with soap and water should be a regular protocol after exposure to soil and dust.

Treatment

The treatment is usually done by Amphotericin B , Posaconazole or Isavuconazole followed by surgical removal of fungal area. Some of the Recent COVID 19 patients in India who got infected with mucomycosis sacrifice their eye to prevent further dissemination to brain.

Conflicts of Interest

All contributing authors declare no conflicts of interest..

References

1 

Center for disease control and prevention. Mucomycosis [Internet]; [updated 2021; cited 2021 May 23]. https://www.cdc.gov/fungal/diseases/mucormycosis/index.html

2 

Wikipedia, the free encyclopedia. Mucomycosis [Internet]; [updated 2021; cited 2021 May 23]. https://en.wikipedia.org/wiki/Mucormycosis



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Article type

Editorial


Article page

1-2


Authors Details

Annapurna Ahuja


Article History

Received : 05-03-2021

Accepted : 12-04-2021


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